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List of anti-seizure medication

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Here is a list of anti-seizure medication (ASM)s.

Each medication listed below includes a link to information about which types of seizures the ASMs are used for, doses, and possible side effects from the electronic Medicines Compendium (eMC), where you can view the patient information leaflet (PIL).

You can find further information in the NICE guideline. NICE is an independent organisation that provides national guidance to improve health and social care services in England.

Click on the links below to search for information about ASMs:

  • by the generic name of the ASM
  • by the brand name of the particular type of ASM.

Generic names with brand names

Please note:

  • Valproate: Sodium valproate, Valproic acid and Topiramate must not be used in females of childbearing potential unless the conditions of the Pregnancy Prevention Programme are met and alternative treatments are ineffective or not tolerated. During pregnancy, they must not be used for epilepsy unless it is the only possible treatment.
  • A first line ASM is an ASM that is tried first. Some ASMs added to a first line ASM are called second line ASMs.
  • ASMs are not split into first and second line for treating children age 12 and under. 
  • Treatment of neonatal seizures (from birth to 28 days of age) is not covered.
  • ‘Effective’ means the seizures it works for. ‘Monotherapy’ means the ASM is taken on its own. ‘Adjunctive' or 'Add-on therapy’ means the ASM is taken alongside other ASM. ‘Tolerance’ means that a drug becomes less effective the longer you take it. A 'tertiary epilepsy specialist' is a specialist with particular expertise and training in epilepsy. 'idiopathic epilepsy' is where someone's epilepsy is genetic or inherited.
  • Information for this page comes from the electronic Medicines Compendium (eMC). 
  • Every effort is made to ensure that all information is correct at time of publishing but information may change after publishing. This information is a guide only and is not a substitute for advice from your doctor. Epilepsy Society is not responsible for any actions taken as a result of using this information.

Information updated: March 2026. Review date: March 2028

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Sodium valproate

Sodium valproate is an epilepsy drug prescribed for all seizure types including absence, myoclonus and tonic clonic seizures. New regulations have been introduced by the Medicines and Healthcare products Regulatory Agency (MHRA) around the way in which the drug, sodium valproate is prescribed to women and girls of childbearing age. 

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